Table 1

Size and position of chromatin domains at neocentromeres.

Cell Line

Domain

Size (kb)

Coord (hg18) chromosome 13

P value

BBB

CENP-A major

89.7

101,901,496-101,991,165

<10^-5*

BBB

CENP-A minor

19

102,140,584-102,159,277

BBB

Intervening

142

101,998,994-102,140,584

BBB

CENP-C major

89.7

101,901,496-101,991,165

<10^-5

BBB

CENP-C minor

19

102,140,584-102,159,277

<10^-5

BBB

H3K4me2

0.740

101,969,955-101,970,694

<10^-5

BBB

H3K9me3

15

102,183,799-102,198,988

<2.5 × 10^-5

BBB

HP1α

15

102,183,799-102,198,988

<5.6 × 10^-5

BBB

HP1γ

15

102,183,799-102,198,988

<9.6 × 10^-5

IMS13q

CENP-A major

90

96,511,130-96,601,103

<10^-5

IMS13q

CENP-A minor

15

96,661,230-96,676,244

IMS13q

Intervening

60

96,601,103-96,661,230

IMS13q

H3K4me2

1.8

96,575,232-96,577,051

<10^-5

IMS13q

H3K9me3

159.5

102,375,370-102,531,950

<10^-5

CHOP13q

CENP-A major

74

70,735,337-70,809,172

<10^-5

CHOP13q

CENP-A minor

10

70,872,442-70,883,219

CHOP13q

intervening

64

70,809,175-70,872,440

CHOP13q

H3K4me2

0.7

70,763,283-70,763,914

<10^-5

*CENP-A major, minor and intervening domains are from same CENP-A ChIP for each cell line, and therefore are determined using same p value.

Alonso et al. Epigenetics & Chromatin 2010 3:6   doi:10.1186/1756-8935-3-6