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1.

2007
Accesses

Research   Open Access Highly Accessed

DNA methylation and transcriptional noise

Iksoo Huh, Jia Zeng, Taesung Park, Soojin V Yi Epigenetics & Chromatin 2013, 6:9 (26 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

1529
Accesses

Review   Open Access Highly Accessed

5-hydroxymethylcytosine and its potential roles in development and cancer

Gerd P Pfeifer, Swati Kadam, Seung-Gi Jin Epigenetics & Chromatin 2013, 6:10 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

1145
Accesses

Research   Open Access

The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing

Elsa Boudadi, Hannah Stower, John A Halsall, Charlotte E Rutledge, Martin Leeb, Anton Wutz, Laura P O’Neill, Karl P Nightingale, Bryan M Turner Epigenetics & Chromatin 2013, 6:11 (1 May 2013)

Abstract | Full text | PDF | PubMed

4.

847
Accesses

Research   Open Access Highly Accessed

Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development

Kelly M Bush, Benjamin TK Yuen, Bonnie L Barrilleaux, John W Riggs, Henriette O’Geen, Rebecca F Cotterman, Paul S Knoepfler Epigenetics & Chromatin 2013, 6:7 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

777
Accesses

Research   Open Access Highly Accessed

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

Magda E Price, Allison M Cotton, Lucia L Lam, Pau Farré, Eldon Emberly, Carolyn J Brown, Wendy P Robinson, Michael S Kobor Epigenetics & Chromatin 2013, 6:4 (3 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

690
Accesses

Research   Open Access Highly Accessed

Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters

Surabhi Srivastava, Deepika Puri, Hita Garapati, Jyotsna Dhawan, Rakesh K Mishra Epigenetics & Chromatin 2013, 6:8 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

619
Accesses

Review   Open Access Highly Accessed

Mitotic bookmarking by transcription factors

Stephan Kadauke, Gerd A Blobel Epigenetics & Chromatin 2013, 6:6 (2 April 2013)

Abstract | Full text | PDF | PubMed

8.

602
Accesses

Research   Open Access

Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain

Rick van Nuland, Frederik MA van Schaik, Marieke Simonis, Sebastiaan van Heesch, Edwin Cuppen, Rolf Boelens, HT Timmers, Hugo van Ingen Epigenetics & Chromatin 2013, 6:12 (8 May 2013)

Abstract | Full text | PDF | PubMed

9.

584
Accesses

Methodology   Open Access

Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene

Ida LM Candiloro, Thomas Mikeska, Peter Hokland, Alexander Dobrovic Epigenetics & Chromatin 2008, 1:7 (3 November 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

488
Accesses

Research   Open Access

Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

Adrienne Grzenda, Gwen Lomberk, Phyllis Svingen, Angela Mathison, Ezequiel Calvo, Juan Iovanna, Yuning Xiong, William Faubion, Raul Urrutia Epigenetics & Chromatin 2013, 6:3 (28 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

474
Accesses

Research   Open Access Highly Accessed

HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes

Jerome Jullien, Carolina Astrand, Emmanuelle Szenker, Nigel Garrett, Genevieve Almouzni, John B Gurdon Epigenetics & Chromatin 2012, 5:17 (29 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The most recent findings from October 2012 Nobel prize winner, John Gurdon, and his lab group. This article describes the necessary deposition of histone H3.3 in order to reprogram somatic cells into pluripotent cells.

12.

449
Accesses

Research   Open Access

A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation

Aneta Bulic, Jan Postberg, Andreas Fischer, Franziska Jönsson, Günter Reuter, Hans J Lipps Epigenetics & Chromatin 2013, 6:5 (5 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

431
Accesses

Editorial   Open Access Highly Accessed

Epigenetics & Chromatin: interactions and processes

Steven Henikoff, Frank Grosveld Epigenetics & Chromatin 2013, 6:2 (27 February 2013)

Abstract | Full text | PDF | PubMed

14.

406
Accesses

Review   Open Access Highly Accessed

A unified phylogeny-based nomenclature for histone variants

Paul B Talbert, Kami Ahmad, Geneviève Almouzni, Juan Ausió, Frederic Berger, Prem L Bhalla, William M Bonner, W Cande, Brian P Chadwick, Simon W L Chan, George A M Cross, Liwang Cui, Stefan I Dimitrov, Detlef Doenecke, José M Eirin-López, Martin A Gorovsky, Sandra B Hake, Barbara A Hamkalo, Sarah Holec, Steven E Jacobsen, Kinga Kamieniarz, Saadi Khochbin, Andreas G Ladurner, David Landsman, John A Latham, Benjamin Loppin, Harmit S Malik, William F Marzluff, John R Pehrson, Jan Postberg et al. Epigenetics & Chromatin 2012, 5:7 (31 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In response to an urgent need to rationalize the current schemes for naming histone variants, researchers from over 30 institutions worldwide have developed consistent but flexible naming rules that are informative and database-searchable.

15.

404
Accesses

Review   Open Access Highly Accessed

Chromatin structure and DNA damage repair

Christoffel Dinant, Adriaan B Houtsmuller, Wim Vermeulen Epigenetics & Chromatin 2008, 1:9 (12 November 2008)

Abstract | Full text | PDF | PubMed

16.

368
Accesses

Research   Open Access Highly Accessed

Genome-wide DNA methylation profiling of non-small cell lung carcinomas

Rejane Carvalho, Vanja Haberle, Jun Hou, Teus van Gent, Supat Thongjuea, Wilfred van IJcken, Christel Kockx, Rutger Brouwer, Erikjan Rijkers, Anieta Sieuwerts, John Foekens, Mirjam van Vroonhoven, Joachim Aerts, Frank Grosveld, Boris Lenhard, Sjaak Philipsen Epigenetics & Chromatin 2012, 5:9 (22 June 2012)

Abstract | Full text | PDF | PubMed

17.

364
Accesses

Research   Open Access

Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

Konstantin Lepikhov, Valeri Zakhartchenko, Ru Hao, Feikun Yang, Christine Wrenzycki, Heiner Niemann, Eckhard Wolf, Joern Walter Epigenetics & Chromatin 2008, 1:8 (3 November 2008)

Abstract | Full text | PDF | PubMed

18.

354
Accesses

Research   Open Access

ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes

Adam Blattler, Lijing Yao, Yao Wang, Zhenqing Ye, Victor X Jin, Peggy J Farnham Epigenetics & Chromatin 2013, 6:13 (21 May 2013)

Abstract | Full text | PDF | PubMed

19.

321
Accesses

Review   Open Access Highly Accessed

Talking to chromatin: post-translational modulation of polycomb group function

Hanneke EC Niessen, Jeroen A Demmers, Jan Voncken Epigenetics & Chromatin 2009, 2:10 (1 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

319
Accesses

Review   Open Access Highly Accessed

ATP-dependent chromatin remodeling in the DNA-damage response

Hannes Lans, Jurgen A Marteijn, Wim Vermeulen Epigenetics & Chromatin 2012, 5:4 (30 January 2012)

Abstract | Full text | PDF | PubMed

21.

318
Accesses

Research   Open Access

Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4

Ingrid Kassner, Marc Barandun, Monika Fey, Florian Rosenthal, Michael O Hottiger Epigenetics & Chromatin 2013, 6:1 (5 January 2013)

Abstract | Full text | PDF | PubMed

22.

306
Accesses

Research   Open Access Highly Accessed

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis

Stefan Glaser, Sandra Lubitz, Kate L Loveland, Kazu Ohbo, Lorraine Robb, Frieder Schwenk, Jost Seibler, Daniela Roellig, Andrea Kranz, Konstantinos Anastassiadis, A Francis Stewart Epigenetics & Chromatin 2009, 2:5 (6 April 2009)

Abstract | Full text | PDF | PubMed

23.

298
Accesses

Research   Open Access Highly Accessed

Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue

Kathryn Woodfine, Joanna E Huddleston, Adele Murrell Epigenetics & Chromatin 2011, 4:1 (31 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

279
Accesses

Methodology   Open Access Highly Accessed

Rapid genome-scale mapping of chromatin accessibility in tissue

Lars Grøntved, Russell Bandle, Sam John, Songjoon Baek, Hye-Jung Chung, Ying Liu, Greti Aguilera, Carl Oberholtzer, Gordon L Hager, David Levens Epigenetics & Chromatin 2012, 5:10 (26 June 2012)

Abstract | Full text | PDF | PubMed

25.

279
Accesses

Research   Open Access Highly Accessed

H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

Irina A Maksakova, Preeti Goyal, Jörn Bullwinkel, Jeremy P Brown, Misha Bilenky, Dixie L Mager, Prim B Singh, Matthew C Lorincz Epigenetics & Chromatin 2011, 4:12 (20 July 2011)

Abstract | Full text | PDF | PubMed

26.

275
Accesses

Research   Open Access Highly Accessed

Tissue-specific variation in DNA methylation levels along human chromosome 1

Cecilia De Bustos, Edward Ramos, Janet M Young, Robert K Tran, Uwe Menzel, Cordelia F Langford, Evan E Eichler, Li Hsu, Steve Henikoff, Jan P Dumanski, Barbara J Trask Epigenetics & Chromatin 2009, 2:7 (8 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

271
Accesses

Research   Open Access Highly Accessed

Trans-generational epigenetic regulation of C. elegans primordial germ cells

Hirofumi Furuhashi, Teruaki Takasaki, Andreas Rechtsteiner, Tengguo Li, Hiroshi Kimura, Paula M Checchi, Susan Strome, William G Kelly Epigenetics & Chromatin 2010, 3:15 (12 August 2010)

Abstract | Full text | PDF | PubMed

28.

270
Accesses

Review   Open Access Highly Accessed

Enhancers and silencers: an integrated and simple model for their function

Petros Kolovos, Tobias A Knoch, Frank G Grosveld, Peter R Cook, Argyris Papantonis Epigenetics & Chromatin 2012, 5:1 (9 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

269
Accesses

Research   Open Access Highly Accessed

CTCF regulates the local epigenetic state of ribosomal DNA repeats

Suzanne van de Nobelen, Manuel Rosa-Garrido, Joerg Leers, Helen Heath, Widia Soochit, Linda Joosen, Iris Jonkers, Jeroen Demmers, Michael van der Reijden, Verónica Torrano, Frank Grosveld, M Dolores Delgado, Rainer Renkawitz, Niels Galjart, Frank Sleutels Epigenetics & Chromatin 2010, 3:19 (8 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

30.

255
Accesses

Research   Open Access Highly Accessed

Distinguishing epigenetic marks of developmental and imprinting regulation

Kirsten R McEwen, Anne C Ferguson-Smith Epigenetics & Chromatin 2010, 3:2 (15 January 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

247
Accesses

Research   Open Access

Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation

Y Amy Tang, Derek Huntley, Giovanni Montana, Andrea Cerase, Tatyana B Nesterova, Neil Brockdorff Epigenetics & Chromatin 2010, 3:10 (7 May 2010)

Abstract | Full text | PDF | PubMed | F1000 Biology

32.

224
Accesses

Research   Open Access

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells

Lovorka Stojic, Zuzana Jasencakova, Carolina Prezioso, Alexandra Stützer, Beatrice Bodega, Diego Pasini, Rebecca Klingberg, Chiara Mozzetta, Raphael Margueron, Pier Puri, Dirk Schwarzer, Kristian Helin, Wolfgang Fischle, Valerio Orlando Epigenetics & Chromatin 2011, 4:16 (5 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

223
Accesses

Review   Open Access Highly Accessed

The influence of DNA sequence on epigenome-induced pathologies

Richard B Meagher, Kristofer J Müssar Epigenetics & Chromatin 2012, 5:11 (20 July 2012)

Abstract | Full text | PDF | PubMed

34.

218
Accesses

Research   Open Access Highly Accessed

Generation of bivalent chromatin domains during cell fate decisions

Marco De Gobbi, David Garrick, Magnus Lynch, Douglas Vernimmen, Jim R Hughes, Nicolas Goardon, Sidinh Luc, Karen M Lower, Jacqueline A Sloane-Stanley, Cristina Pina, Shamit Soneji, Raffaele Renella, Tariq Enver, Stephen Taylor, Sten Eirik W Jacobsen, Paresh Vyas, Richard J Gibbons, Douglas R Higgs Epigenetics & Chromatin 2011, 4:9 (6 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The hypothesis that bivalently modified genes are pre-marked for subsequent activation during differentiation is questioned as being over-simplistic, as further light is shed on the generation of bivalent chromatin domains during cell fate decisions.

35.

219
Accesses

Methodology   Open Access

Tracking the mechanical dynamics of human embryonic stem cell chromatin

Elizabeth Hinde, Francesco Cardarelli, Aaron Chen, Michelle Khine, Enrico Gratton Epigenetics & Chromatin 2012, 5:20 (21 December 2012)

Abstract | Full text | PDF | PubMed

36.

213
Accesses

Methodology   Open Access Highly Accessed

Global turnover of histone post-translational modifications and variants in human cells

Barry M Zee, Rebecca S Levin, Peter A DiMaggio, Benjamin A Garcia Epigenetics & Chromatin 2010, 3:22 (6 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

215
Accesses

Research   Open Access Highly Accessed

Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes

Kazutaka Murata, Tony Kouzarides, Andrew J Bannister, John B Gurdon Epigenetics & Chromatin 2010, 3:4 (4 February 2010)

Abstract | Full text | PDF | PubMed

38.

211
Accesses

Research   Open Access

ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage

Leng-Siew Yeap, Katsuhiko Hayashi, M Azim Surani Epigenetics & Chromatin 2009, 2:12 (7 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

39.

209
Accesses

Research   Open Access

High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model

Maartje J Vogel, Ludo Pagie, Wendy Talhout, Marja Nieuwland, Ron M Kerkhoven, Bas van Steensel Epigenetics & Chromatin 2009, 2:1 (29 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

40.

212
Accesses

Methodology   Open Access

Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies

Ryan KC Yuen, Ruby Jiang, Maria S Peñaherrera, Deborah E McFadden, Wendy P Robinson Epigenetics & Chromatin 2011, 4:10 (13 July 2011)

Abstract | Full text | PDF | PubMed

41.

197
Accesses

Research   Open Access

An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo

Lia E Gracey, Zhi-Ying Chen, Jay M Maniar, Anton Valouev, Arend Sidow, Mark A Kay, Andrew Z Fire Epigenetics & Chromatin 2010, 3:13 (1 July 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The introduction of a synthetic high-affinity nucleosome-positioning signal into a DNA plasmid vector in mice results in the strong yet transient positioning of nucleosomes in vivo.

42.

197
Accesses

Research   Open Access

Selected imprinting of INS in the marsupial

Jessica M Stringer, Shunsuke Suzuki, Andrew J Pask, Geoff Shaw, Marilyn B Renfree Epigenetics & Chromatin 2012, 5:14 (28 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

INS, the gene encoding insulin, is imprinted in the mammary gland, suggesting a role for genomic imprinting during lactation which may be as critical for post-natal growth in mammals as imprinting in the placenta is pre-natally.

43.

190
Accesses

Research   Open Access

Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae

Esther R Loney, Peter W Inglis, Sarah Sharp, Fiona E Pryde, Nicholas A Kent, Jane Mellor, Edward J Louis Epigenetics & Chromatin 2009, 2:18 (2 December 2009)

Abstract | Full text | PDF | PubMed

44.

185
Accesses

Research   Open Access Highly Accessed

The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

Frank Sleutels, Widia Soochit, Marek Bartkuhn, Helen Heath, Sven Dienstbach, Philipp Bergmaier, Vedran Franke, Manuel Rosa-Garrido, Suzanne van de Nobelen, Lisa Caesar, Michael van der Reijden, Jan Bryne, Wilfred van IJcken, J Grootegoed, M Delgado, Boris Lenhard, Rainer Renkawitz, Frank Grosveld, Niels Galjart Epigenetics & Chromatin 2012, 5:8 (18 June 2012)

Abstract | Full text | PDF | PubMed

45.

185
Accesses

Research   Open Access

Mediator regulates non-coding RNA transcription at fission yeast centromeres

Michael Thorsen, Heidi Hansen, Michela Venturi, Steen Holmberg, Genevieve Thon Epigenetics & Chromatin 2012, 5:19 (21 November 2012)

Abstract | Full text | PDF | PubMed

46.

182
Accesses

Research   Open Access

Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells

Natalia Varlakhanova, Rebecca Cotterman, Keith Bradnam, Ian Korf, Paul S Knoepfler Epigenetics & Chromatin 2011, 4:20 (4 November 2011)

Abstract | Full text | PDF | PubMed

47.

176
Accesses

Research   Open Access Highly Accessed

Extensive epigenetic reprogramming in human somatic tissues between fetus and adult

Ryan KC Yuen, Sarah MA Neumann, Alexandra K Fok, Maria S Peñaherrera, Deborah E McFadden, Wendy P Robinson, Michael S Kobor Epigenetics & Chromatin 2011, 4:7 (5 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

167
Accesses

Research   Open Access

Transcription-dependent silencing of inducible convergent transgenes in transgenic mice

Fernando J Calero-Nieto, Andrew G Bert, Peter N Cockerill Epigenetics & Chromatin 2010, 3:3 (19 January 2010)

Abstract | Full text | PDF | PubMed

49.

168
Accesses

Research   Open Access

Deacetylation of H4-K16Ac and heterochromatin assembly in senescence

Kévin Contrepois, Jean-Yves Thuret, Régis Courbeyrette, François Fenaille, Carl Mann Epigenetics & Chromatin 2012, 5:15 (29 August 2012)

Abstract | Full text | PDF | PubMed

50.

164
Accesses

Research   Open Access

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

Shuying He, Melinda K Pirity, Wei-Lin Wang, Louise Wolf, Bharesh K Chauhan, Kveta Cveklova, Ernst R Tamm, Ruth Ashery-Padan, Daniel Metzger, Akira Nakai, Pierre Chambon, Jiri Zavadil, Ales Cvekl Epigenetics & Chromatin 2010, 3:21 (30 November 2010)

Abstract | Full text | PDF | PubMed

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